Adaptation of gastric lipase in mini-pigs fed a high-fat diet
Identifieur interne : 000160 ( France/Analysis ); précédent : 000159; suivant : 000161Adaptation of gastric lipase in mini-pigs fed a high-fat diet
Auteurs : M. Armand [France] ; P. Borel [France] ; P. H. Rolland [France] ; M. Senft [France] ; M. André [France] ; H. Lafont [France] ; D. Lairon [France]Source :
- Nutrition Research [ 0271-5317 ] ; 1992.
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Abstract
This report describes the changes in two lipolytic enzyme activities in mini-pigs, i.e. gastric lipase and colipase-dependant pancreatic lipase, in response to diets with different fat contents. The animals were divided into two groups, one consuming a diet containing 2% fat, the other 34% fat. In fasted animals, gastric lipase was essentially only found in the fundic mucosa. When compared to the low-fat fed animals, the tissue activity and specific activity of the gastric lipase was significantly increased (by 88.7 and 85.2%, respectively). Pancreatic lipase activity exhibited a rise generally observed under fat feeding. The ratio of gastric to pancreatic lipase activity was low in the mini-pig and was not altered by dietary fat. In conclusion, as observed in the rat and the rabbit, the preduodenal lipase of the mini-pig adapts to the level of dietary fat.
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DOI: 10.1016/S0271-5317(05)80019-3
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ISTEX:4BDD73D1D9F9DDEEDDF0E74E085F8E1E250A94FALe document en format XML
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The animals were divided into two groups, one consuming a diet containing 2% fat, the other 34% fat. In fasted animals, gastric lipase was essentially only found in the fundic mucosa. When compared to the low-fat fed animals, the tissue activity and specific activity of the gastric lipase was significantly increased (by 88.7 and 85.2%, respectively). Pancreatic lipase activity exhibited a rise generally observed under fat feeding. The ratio of gastric to pancreatic lipase activity was low in the mini-pig and was not altered by dietary fat. In conclusion, as observed in the rat and the rabbit, the preduodenal lipase of the mini-pig adapts to the level of dietary fat.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Provence-Alpes-Côte d'Azur</li></region><settlement><li>Marseille</li></settlement></list><tree><country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Armand, M" sort="Armand, M" uniqKey="Armand M" first="M." last="Armand">M. Armand</name></region><name sortKey="Andre, M" sort="Andre, M" uniqKey="Andre M" first="M." last="André">M. André</name><name sortKey="Borel, P" sort="Borel, P" uniqKey="Borel P" first="P." last="Borel">P. Borel</name><name sortKey="Lafont, H" sort="Lafont, H" uniqKey="Lafont H" first="H." last="Lafont">H. Lafont</name><name sortKey="Lairon, D" sort="Lairon, D" uniqKey="Lairon D" first="D." last="Lairon">D. Lairon</name><name sortKey="Rolland, P H" sort="Rolland, P H" uniqKey="Rolland P" first="P. H." last="Rolland">P. H. 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